Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EW...
Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions
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Author / Creator
Övriga starka forskningsmiljöer , Faculty of Medicine , Medicinska fakulteten , Other Strong Research Environments , LUCC: Lund University Cancer Centre , Division of Clinical Genetics , Department of Laboratory Medicine , Avdelningen för klinisk genetik , Pathways of cancer cell evolution , Institutionen för kliniska vetenskaper, Lund , Lunds universitet , Department of Clinical Sciences, Lund , Childhood Cancer Research Unit , Profilområden och andra starka forskningsmiljöer , Paediatrics (Lund) , Lund University , Institutionen för laboratoriemedicin , Sektion V , Pediatrik, Lund , Profile areas and other strong research environments , Section V , Cancercellers evolution , LUCC: Lunds universitets cancercentrum , Schöpf, Julia , Uhrig, Sebastian , Heilig, Christoph E. , Lee, Kwang-Seok , Walther, Tatjana , Carazzato, Alexander , Dobberkau, Anna Maria , Weichenhan, Dieter , Plass, Christoph , Hartmann, Mark , Diwan, Gaurav D. , Carrero, Zunamys I. , Ball, Claudia R. , Hohl, Tobias , Kindler, Thomas , Rudolph-Hähnel, Patricia , Helm, Dominic , Schneider, Martin , Nilsson, Anna , Øra, Ingrid , Imle, Roland , Banito, Ana , Russell, Robert B. , Jones, Barbara C. , Lipka, Daniel B. , Glimm, Hanno , Hübschmann, Daniel , Hartmann, Wolfgang , Fröhling, Stefan and Scholl, Claudia
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Linking clinical multi-omics with mechanistic studies may improve the understanding of rare cancers. We leverage two precision oncology programs to investigate rhabdomyosarcoma with FUS/EWSR1-TFCP2 fusions, an orphan malignancy without effective therapies. All tumors exhibit outlier ALK expression, partly accompanied by intragenic deletions and abe...
Alternative Titles
Full title
Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions
Authors, Artists and Contributors
Author / Creator
Faculty of Medicine
Medicinska fakulteten
Other Strong Research Environments
LUCC: Lund University Cancer Centre
Division of Clinical Genetics
Department of Laboratory Medicine
Avdelningen för klinisk genetik
Pathways of cancer cell evolution
Institutionen för kliniska vetenskaper, Lund
Lunds universitet
Department of Clinical Sciences, Lund
Childhood Cancer Research Unit
Profilområden och andra starka forskningsmiljöer
Paediatrics (Lund)
Lund University
Institutionen för laboratoriemedicin
Sektion V
Pediatrik, Lund
Profile areas and other strong research environments
Section V
Cancercellers evolution
LUCC: Lunds universitets cancercentrum
Schöpf, Julia
Uhrig, Sebastian
Heilig, Christoph E.
Lee, Kwang-Seok
Walther, Tatjana
Carazzato, Alexander
Dobberkau, Anna Maria
Weichenhan, Dieter
Plass, Christoph
Hartmann, Mark
Diwan, Gaurav D.
Carrero, Zunamys I.
Ball, Claudia R.
Hohl, Tobias
Kindler, Thomas
Rudolph-Hähnel, Patricia
Helm, Dominic
Schneider, Martin
Nilsson, Anna
Øra, Ingrid
Imle, Roland
Banito, Ana
Russell, Robert B.
Jones, Barbara C.
Lipka, Daniel B.
Glimm, Hanno
Hübschmann, Daniel
Hartmann, Wolfgang
Fröhling, Stefan
Scholl, Claudia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2ecd072ff8db496d9a6745bf800ae284
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2ecd072ff8db496d9a6745bf800ae284
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-44360-2
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