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Mechanisms of Sorafenib Resistance in HCC Culture Relate to the Impaired Membrane Expression of Orga...

Mechanisms of Sorafenib Resistance in HCC Culture Relate to the Impaired Membrane Expression of Orga...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2edb80aedf584fb8b12a6694380f2e4c

Mechanisms of Sorafenib Resistance in HCC Culture Relate to the Impaired Membrane Expression of Organic Cation Transporter 1 (OCT1)

About this item

Full title

Mechanisms of Sorafenib Resistance in HCC Culture Relate to the Impaired Membrane Expression of Organic Cation Transporter 1 (OCT1)

Publisher

New Zealand: Dove

Journal title

Journal of hepatocellular carcinoma, 2024-01, Vol.11, p.839-855

Language

English

Formats

Publication information

Publisher

New Zealand: Dove

More information

Scope and Contents

Contents

Sorafenib, an FDA-approved drug for advanced hepatocellular carcinoma (HCC) treatment, encounters resistance in many patients. Deciphering the mechanisms underlying sorafenib resistance is crucial for devising alternative strategies to overcome it.
This study aimed to investigate sorafenib resistance mechanisms using a diverse panel of HCC cell...

Alternative Titles

Full title

Mechanisms of Sorafenib Resistance in HCC Culture Relate to the Impaired Membrane Expression of Organic Cation Transporter 1 (OCT1)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2edb80aedf584fb8b12a6694380f2e4c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2edb80aedf584fb8b12a6694380f2e4c

Other Identifiers

ISSN

2253-5969

E-ISSN

2253-5969

DOI

10.2147/JHC.S452152

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