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FGF23 regulates renal sodium handling and blood pressure

FGF23 regulates renal sodium handling and blood pressure

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2f1a1109b110484487794844480e91b7

FGF23 regulates renal sodium handling and blood pressure

About this item

Full title

FGF23 regulates renal sodium handling and blood pressure

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2014-06, Vol.6 (6), p.744-759

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Fibroblast growth factor‐23 (FGF23) is a bone‐derived hormone regulating renal phosphate reabsorption and vitamin D synthesis in renal proximal tubules. Here, we show that FGF23 directly regulates the membrane abundance of the Na
+
:Cl

co‐transporter NCC in distal renal tubules by a signaling mechanism involving the FGF receptor/αKlot...

Alternative Titles

Full title

FGF23 regulates renal sodium handling and blood pressure

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2f1a1109b110484487794844480e91b7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2f1a1109b110484487794844480e91b7

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.1002/emmm.201303716

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