In Silico Prediction of Alkaline Phosphatase Interaction with the Natural Inhibitory 5-Azaindoles Gu...
In Silico Prediction of Alkaline Phosphatase Interaction with the Natural Inhibitory 5-Azaindoles Guitarrin C and D
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The natural 5-azaindoles, marine sponge guitarrin C and D, were observed to exert inhibitory activity against a highly active alkaline phosphatase (ALP) CmAP of the PhoA family from the marine bacterium
, with IC
values of 8.5 and 110 µM, respectively. The superimposition of CmAP complexes with
-nitrophenyl phosphate (
NPP), a commonly...
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Full title
In Silico Prediction of Alkaline Phosphatase Interaction with the Natural Inhibitory 5-Azaindoles Guitarrin C and D
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TN_cdi_doaj_primary_oai_doaj_org_article_2f1f43873b364ff2915dd2b25b39c313
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2f1f43873b364ff2915dd2b25b39c313
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules29235701
