Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadhe...
Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability
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Author / Creator
Gioelli, Noemi , Neilson, Lisa J. , Wei, Na , Villari, Giulia , Chen, Wenqian , Kuhle, Bernhard , Ehling, Manuel , Maione, Federica , Willox, Sander , Brundu, Serena , Avanzato, Daniele , Koulouras, Grigorios , Mazzone, Massimiliano , Giraudo, Enrico , Yang, Xiang-Lei , Valdembri, Donatella , Zanivan, Sara and Serini, Guido
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The formation of a functional blood vessel network relies on the ability of endothelial cells (ECs) to dynamically rearrange their adhesive contacts in response to blood flow and guidance cues, such as vascular endothelial growth factor-A (VEGF-A) and class 3 semaphorins (SEMA3s). Neuropilin 1 (NRP1) is essential for blood vessel development, indep...
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Full title
Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2f35d1709b354aba9e4278bad5764f45
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2f35d1709b354aba9e4278bad5764f45
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31904-1
