Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in...
Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models
About this item
Full title
Author / Creator
Rossotti, Martin A. , van Faassen, Henk , Tran, Anh T. , Sheff, Joey , Sandhu, Jagdeep K. , Duque, Diana , Hewitt, Melissa , Wen, Xiaoxue , Bavananthasivam, Jegarubee , Beitari, Saina , Matte, Kevin , Laroche, Geneviève , Giguère, Patrick M. , Gervais, Christian , Stuible, Matthew , Guimond, Julie , Perret, Sylvie , Hussack, Greg , Langlois, Marc-André , Durocher, Yves and Tanha, Jamshid
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Nanobodies offer several potential advantages over mAbs for the control of SARS-CoV-2. Their ability to access cryptic epitopes conserved across SARS-CoV-2 variants of concern (VoCs) and feasibility to engineer modular, multimeric designs, make these antibody fragments ideal candidates for developing broad-spectrum therapeutics against current and...
Alternative Titles
Full title
Arsenal of nanobodies shows broad-spectrum neutralization against SARS-CoV-2 variants of concern in vitro and in vivo in hamster models
Authors, Artists and Contributors
Author / Creator
van Faassen, Henk
Tran, Anh T.
Sheff, Joey
Sandhu, Jagdeep K.
Duque, Diana
Hewitt, Melissa
Wen, Xiaoxue
Bavananthasivam, Jegarubee
Beitari, Saina
Matte, Kevin
Laroche, Geneviève
Giguère, Patrick M.
Gervais, Christian
Stuible, Matthew
Guimond, Julie
Perret, Sylvie
Hussack, Greg
Langlois, Marc-André
Durocher, Yves
Tanha, Jamshid
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2f48dc9abf474ef9b75e5e6b1b33d3f4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2f48dc9abf474ef9b75e5e6b1b33d3f4
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-022-03866-z
