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N -Alkylaminoferrocene-Based Prodrugs Targeting Mitochondria of Cancer Cells

N -Alkylaminoferrocene-Based Prodrugs Targeting Mitochondria of Cancer Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2fb24f35e111444aa1b6da2c0e6b94bc

N -Alkylaminoferrocene-Based Prodrugs Targeting Mitochondria of Cancer Cells

About this item

Full title

N -Alkylaminoferrocene-Based Prodrugs Targeting Mitochondria of Cancer Cells

Publisher

Switzerland: MDPI

Journal title

Molecules (Basel, Switzerland), 2020-05, Vol.25 (11), p.2545

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Intracellular concentration of reactive oxygen species (e.g., H
O
) in cancer cells is elevated over 10-fold as compared to normal cells. This feature has been used by us and several other research groups to design cancer specific prodrugs, for example,
-alkylaminoferrocene (NAAF)-based prodrugs. Further improvement of the efficacy of thes...

Alternative Titles

Full title

N -Alkylaminoferrocene-Based Prodrugs Targeting Mitochondria of Cancer Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2fb24f35e111444aa1b6da2c0e6b94bc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2fb24f35e111444aa1b6da2c0e6b94bc

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules25112545

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