Development of folate receptor targeting chimeras for cancer selective degradation of extracellular...
Development of folate receptor targeting chimeras for cancer selective degradation of extracellular proteins
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Targeted protein degradation has emerged as a novel therapeutic modality to treat human diseases by utilizing the cell’s own disposal systems to remove protein target. Significant clinical benefits have been observed for degrading many intracellular proteins. Recently, the degradation of extracellular proteins in the lysosome has been developed. Ho...
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Full title
Development of folate receptor targeting chimeras for cancer selective degradation of extracellular proteins
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TN_cdi_doaj_primary_oai_doaj_org_article_2fb5fe98fda44ef286be9db01fc87726
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2fb5fe98fda44ef286be9db01fc87726
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-52685-9
