Altered dendritic spine function and integration in a mouse model of fragile X syndrome
Altered dendritic spine function and integration in a mouse model of fragile X syndrome
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cellular and circuit hyperexcitability are core features of fragile X syndrome and related autism spectrum disorder models. However, the cellular and synaptic bases of this hyperexcitability have proved elusive. We report in a mouse model of fragile X syndrome, glutamate uncaging onto individual dendritic spines yields stronger single-spine excitat...
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Altered dendritic spine function and integration in a mouse model of fragile X syndrome
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TN_cdi_doaj_primary_oai_doaj_org_article_2fbc40b23b8f4722ab1014116cebc102
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2fbc40b23b8f4722ab1014116cebc102
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11891-6