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Altered dendritic spine function and integration in a mouse model of fragile X syndrome

Altered dendritic spine function and integration in a mouse model of fragile X syndrome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2fbc40b23b8f4722ab1014116cebc102

Altered dendritic spine function and integration in a mouse model of fragile X syndrome

About this item

Full title

Altered dendritic spine function and integration in a mouse model of fragile X syndrome

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-10, Vol.10 (1), p.4813-14, Article 4813

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cellular and circuit hyperexcitability are core features of fragile X syndrome and related autism spectrum disorder models. However, the cellular and synaptic bases of this hyperexcitability have proved elusive. We report in a mouse model of fragile X syndrome, glutamate uncaging onto individual dendritic spines yields stronger single-spine excitat...

Alternative Titles

Full title

Altered dendritic spine function and integration in a mouse model of fragile X syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2fbc40b23b8f4722ab1014116cebc102

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2fbc40b23b8f4722ab1014116cebc102

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-11891-6

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