DUB1 suppresses Hippo signaling by modulating TAZ protein expression in gastric cancer
DUB1 suppresses Hippo signaling by modulating TAZ protein expression in gastric cancer
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Author / Creator
Wang, Dehai , Li, Zhongbo , Li, Xin , Yan, Cheng , Yang, Huijie , Zhuang, Ting , Wang, Xiao , Zang, Yifeng , Liu, Ziping , Wang, Tianshi , Jiang, Rixia , Su, Peng , Zhu, Jian and Ding, Yinlu
Publisher
London: BioMed Central Ltd
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Language
English
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Publisher
London: BioMed Central Ltd
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Contents
Background The Hippo pathway functions as a tumor suppressor pathway in human cancers, while dysfunction of the Hippo pathway is frequently observed in malignancies. Although YAP/TAZ activity is tightly controlled by the phosphorylation cascade of the MST-LATS-YAP/TAZ axis, it is still unclear why the YAP/TAZ proteins are activated in human cancers...
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Full title
DUB1 suppresses Hippo signaling by modulating TAZ protein expression in gastric cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_2fdc017c5a9c4d9aaef1fa5cec6b80ce
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2fdc017c5a9c4d9aaef1fa5cec6b80ce
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-022-02410-5
