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Towards water-soluble [60]fullerenes for the delivery of siRNA in a prostate cancer model

Towards water-soluble [60]fullerenes for the delivery of siRNA in a prostate cancer model

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2ff5f227aeb34945a7460424bb027439

Towards water-soluble [60]fullerenes for the delivery of siRNA in a prostate cancer model

About this item

Full title

Towards water-soluble [60]fullerenes for the delivery of siRNA in a prostate cancer model

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-05, Vol.11 (1), p.10565-10565, Article 10565

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

This paper presents two water-soluble fullerene nanomaterials (HexakisaminoC
60
and monoglucosamineC
60
, which is called here JK39) that were developed and synthesized as non-viral siRNA transfection nanosystems. The developed two-step Bingel–Hirsch reaction enables the chemical modification of the fullerene scaffold with the desired b...

Alternative Titles

Full title

Towards water-soluble [60]fullerenes for the delivery of siRNA in a prostate cancer model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2ff5f227aeb34945a7460424bb027439

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2ff5f227aeb34945a7460424bb027439

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-89943-5

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