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The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized m...

The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized m...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3002e9bc15314a328ef2addfdebb3e67

The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice

About this item

Full title

The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice

Publisher

England: BioMed Central

Journal title

BMC genomics, 2018-06, Vol.19 (1), p.443-443, Article 443

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

The role of PPARα in gene regulation in mouse liver is well characterized. However, less is known about the role of PPARα in human liver. The aim of the present study was to better characterize the impact of PPARα activation on gene regulation in human liver. To that end, chimeric mice containing hepatocyte humanized livers were given an oral dose...

Alternative Titles

Full title

The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3002e9bc15314a328ef2addfdebb3e67

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3002e9bc15314a328ef2addfdebb3e67

Other Identifiers

ISSN

1471-2164

E-ISSN

1471-2164

DOI

10.1186/s12864-018-4834-3

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