SF3B1 inhibition disrupts malignancy and prolongs survival in glioblastoma patients through BCL2L1 s...
SF3B1 inhibition disrupts malignancy and prolongs survival in glioblastoma patients through BCL2L1 splicing and mTOR/ß-catenin pathways imbalances
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Glioblastoma is one of the most devastating cancer worldwide based on its locally aggressive behavior and because it cannot be cured by current therapies. Defects in alternative splicing process are frequent in cancer. Recently, we demonstrated that dysregulation of the spliceosome is directly associated with glioma development, progression, and ag...
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SF3B1 inhibition disrupts malignancy and prolongs survival in glioblastoma patients through BCL2L1 splicing and mTOR/ß-catenin pathways imbalances
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TN_cdi_doaj_primary_oai_doaj_org_article_302009fc920f44f29ce38b09cfabbfd1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_302009fc920f44f29ce38b09cfabbfd1
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-022-02241-4
