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Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways

Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_307f7bb2bfd94ea8941c99afedc14e8e

Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways

About this item

Full title

Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways

Publisher

United States: Public Library of Science (PLoS)

Journal title

PloS one, 2010-12, Vol.5 (12), p.e15805-e15805

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science (PLoS)

More information

Scope and Contents

Contents

Canonical ubiquitin-like proteins (UBLs) such as ubiquitin, Sumo, NEDD8, and ISG15 are ligated to targets by E1-E2-E3 multienzyme cascades. The Sumo cascade, conserved among all eukaryotes, regulates numerous biological processes including protein localization, transcription, DNA replication, and mitosis. Sumo conjugation is initiated by the hetero...

Alternative Titles

Full title

Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_307f7bb2bfd94ea8941c99afedc14e8e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_307f7bb2bfd94ea8941c99afedc14e8e

Other Identifiers

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0015805

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