The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma
The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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The pursuit of matrix metalloproteinase (MMP) inhibitors began in earnest over three decades ago. Initial clinical trials were disappointing, resulting in a negative view of MMPs as therapeutic targets. As a better understanding of MMP biology and inhibitor pharmacokinetic properties emerged, it became clear that initial MMP inhibitor clinical tria...
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The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma
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TN_cdi_doaj_primary_oai_doaj_org_article_30a1b97bd0c94e56af12e7b80f1caea3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_30a1b97bd0c94e56af12e7b80f1caea3
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells8090984