Booster immunizations with DNA plasmids encoding HER-2/neu prevent spontaneous mammary cancer in HER...
Booster immunizations with DNA plasmids encoding HER-2/neu prevent spontaneous mammary cancer in HER-2/neu transgenic mice over life span
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cancer vaccines are less effective at old than at young age because of immunosenescence. Besides, in preliminary observations we showed that the immunization with HER-2/neu DNA plasmid in transgenic young mice (standard immunization, SI) delays but not abrogate spontaneous mammary tumours progressively appearing during aging. In this study we evalu...
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Booster immunizations with DNA plasmids encoding HER-2/neu prevent spontaneous mammary cancer in HER-2/neu transgenic mice over life span
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TN_cdi_doaj_primary_oai_doaj_org_article_30a26d3f0af04239af09033dd04f3b15
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_30a26d3f0af04239af09033dd04f3b15
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-03286-8
