TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthrit...
TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models
About this item
Full title
Author / Creator
Wu, Jiao , Feng, Zhuan , Chen, Liang , Li, Yong , Bian, Huijie , Geng, Jiejie , Zheng, Zhao-Hui , Fu, Xianghui , Pei, Zhuo , Qin, Yifei , Yang, Liu , Zhao, Yilin , Wang, Ke , Chen, Ruo , He, Qian , Nan, Gang , Jiang, Xuejun , Chen, Zhi-Nan and Zhu, Ping
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Ferroptosis is a nonapoptotic cell death process that requires cellular iron and the accumulation of lipid peroxides. In progressive rheumatoid arthritis (RA), synovial fibroblasts proliferate abnormally in the presence of reactive oxygen species (ROS) and elevated lipid oxidation. Here we show, using a collagen-induced arthritis (CIA) mouse model,...
Alternative Titles
Full title
TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_30a3aee147db4af3aa058615f826173a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_30a3aee147db4af3aa058615f826173a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27948-4
