Mechanistic target of rapamycin (mTOR) pathway in Sertoli cells regulates age-dependent changes in s...
Mechanistic target of rapamycin (mTOR) pathway in Sertoli cells regulates age-dependent changes in sperm DNA methylation
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Publisher
England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Over the past several decades, a trend toward delayed childbirth has led to increases in parental age at the time of conception. Sperm epigenome undergoes age-dependent changes increasing risks of adverse conditions in offspring conceived by fathers of advanced age. The mechanism(s) linking paternal age with epigenetic changes in sperm remain unkno...
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Full title
Mechanistic target of rapamycin (mTOR) pathway in Sertoli cells regulates age-dependent changes in sperm DNA methylation
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TN_cdi_doaj_primary_oai_doaj_org_article_30b3cc2e57514122a082c0126d9ffdf2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_30b3cc2e57514122a082c0126d9ffdf2
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.90992
