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Flagellar cAMP signaling controls trypanosome progression through host tissues

Flagellar cAMP signaling controls trypanosome progression through host tissues

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_30f4254f1f9248b0a285b1c1494715d5

Flagellar cAMP signaling controls trypanosome progression through host tissues

About this item

Full title

Flagellar cAMP signaling controls trypanosome progression through host tissues

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-02, Vol.10 (1), p.803-803, Article 803

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The unicellular parasite
Trypanosoma brucei
is transmitted between mammals by tsetse flies. Following the discovery that flagellar phosphodiesterase PDEB1 is required for trypanosomes to move in response to signals in vitro (social motility), we investigated its role in tsetse flies. Here we show that PDEB1 knockout parasites exhibit subtle c...

Alternative Titles

Full title

Flagellar cAMP signaling controls trypanosome progression through host tissues

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_30f4254f1f9248b0a285b1c1494715d5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_30f4254f1f9248b0a285b1c1494715d5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-08696-y

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