Flagellar cAMP signaling controls trypanosome progression through host tissues
Flagellar cAMP signaling controls trypanosome progression through host tissues
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The unicellular parasite
Trypanosoma brucei
is transmitted between mammals by tsetse flies. Following the discovery that flagellar phosphodiesterase PDEB1 is required for trypanosomes to move in response to signals in vitro (social motility), we investigated its role in tsetse flies. Here we show that PDEB1 knockout parasites exhibit subtle c...
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Flagellar cAMP signaling controls trypanosome progression through host tissues
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TN_cdi_doaj_primary_oai_doaj_org_article_30f4254f1f9248b0a285b1c1494715d5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_30f4254f1f9248b0a285b1c1494715d5
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-08696-y