Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-...
Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity
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Author / Creator
Salvi, Valentina , Gaudenzi, Carolina , Mariotti, Barbara , Giongrandi, Gaia , Alacqua, Silvia , Gianello, Veronica , Schioppa, Tiziana , Tiberio, Laura , Ceribelli, Angela , Selmi, Carlo , Bergese, Paolo , Calza, Stefano , Del Prete, Annalisa , Sozzani, Silvano , Bazzoni, Flavia and Bosisio, Daniela
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The physiological relevance of cell-to-cell communication mediated by small extracellular vesicle-encapsulated microRNAs (sEV-miRNAs) remains debated because of the limiting representativity of specific miRNAs within the extracellular pool. We hypothesize that sEV-miRNA non-canonical function consisting of the stimulation of Toll-like receptor 7 (T...
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Full title
Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_314b902687d6416e8812b09c4914d5db
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_314b902687d6416e8812b09c4914d5db
Other Identifiers
ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-024-01924-z
