Formin-like 1β phosphorylation at S1086 is necessary for secretory polarized traffic of exosomes at...
Formin-like 1β phosphorylation at S1086 is necessary for secretory polarized traffic of exosomes at the immune synapse in Jurkat T lymphocytes
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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We analyzed here how formin-like 1 β (FMNL1β), an actin cytoskeleton-regulatory protein, regulates microtubule-organizing center (MTOC) and multivesicular bodies (MVB) polarization and exosome secretion at an immune synapse (IS) model in a phosphorylation-dependent manner. IS formation was associated with transient recruitment of FMNL1β to the IS,...
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Formin-like 1β phosphorylation at S1086 is necessary for secretory polarized traffic of exosomes at the immune synapse in Jurkat T lymphocytes
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TN_cdi_doaj_primary_oai_doaj_org_article_3168c622c4ec4754b83f7f11e85f753b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3168c622c4ec4754b83f7f11e85f753b
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.96942
