Deubiquitinating enzymes and the proteasome regulate preferential sets of ubiquitin substrates
Deubiquitinating enzymes and the proteasome regulate preferential sets of ubiquitin substrates
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The ubiquitin-proteasome axis has been extensively explored at a system-wide level, but the impact of deubiquitinating enzymes (DUBs) on the ubiquitinome remains largely unknown. Here, we compare the contributions of the proteasome and DUBs on the global ubiquitinome, using UbiSite technology, inhibitors and mass spectrometry. We uncover large dyna...
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Full title
Deubiquitinating enzymes and the proteasome regulate preferential sets of ubiquitin substrates
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TN_cdi_doaj_primary_oai_doaj_org_article_31d21d51d10f47c7b838fbd4612da909
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_31d21d51d10f47c7b838fbd4612da909
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30376-7
