Full-length human GLP-1 receptor structure without orthosteric ligands
Full-length human GLP-1 receptor structure without orthosteric ligands
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Glucagon-like peptide-1 receptor (GLP-1R) is a class B G protein-coupled receptor that plays an important role in glucose homeostasis and treatment of type 2 diabetes. Structures of full-length class B receptors were determined in complex with their orthosteric agonist peptides, however, little is known about their extracellular domain (ECD) confor...
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Full title
Full-length human GLP-1 receptor structure without orthosteric ligands
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TN_cdi_doaj_primary_oai_doaj_org_article_3203b4bbea3845c690168fa0775d64d9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3203b4bbea3845c690168fa0775d64d9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-14934-5
