Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour gro...
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
About this item
Full title
Author / Creator
Lechertier, Tanguy , Reynolds, Louise E. , Kim, Hyojin , Pedrosa, Ana Rita , Gómez-Escudero, Jesús , Muñoz-Félix, José M. , Batista, Silvia , Dukinfield, Matthew , Demircioglu, Fevzi , Wong, Ping Pui , Matchett, Kylie P. , Henderson, Neil C. , D’Amico, Gabriela , Parsons, Maddy , Harwood, Catherine , Meier, Pascal and Hodivala-Dilke, Kairbaan M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The overexpression of the protein tyrosine kinase, Focal adhesion kinase (FAK), in endothelial cells has implicated its requirement in angiogenesis and tumour growth, but how pericyte FAK regulates tumour angiogenesis is unknown. We show that pericyte FAK regulates tumour growth and angiogenesis in multiple mouse models of melanoma, lung carcinoma...
Alternative Titles
Full title
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
Authors, Artists and Contributors
Author / Creator
Reynolds, Louise E.
Kim, Hyojin
Pedrosa, Ana Rita
Gómez-Escudero, Jesús
Muñoz-Félix, José M.
Batista, Silvia
Dukinfield, Matthew
Demircioglu, Fevzi
Wong, Ping Pui
Matchett, Kylie P.
Henderson, Neil C.
D’Amico, Gabriela
Parsons, Maddy
Harwood, Catherine
Meier, Pascal
Hodivala-Dilke, Kairbaan M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_327b0c1e155a4263840ab94acda7cb38
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_327b0c1e155a4263840ab94acda7cb38
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16618-6
