Intermittent-Hypoxia-Induced Autophagy Activation Through the ER-Stress-Related PERK/eIF2α/ATF4 Path...
Intermittent-Hypoxia-Induced Autophagy Activation Through the ER-Stress-Related PERK/eIF2α/ATF4 Pathway is a Protective Response to Pancreatic β-Cell Apoptosis
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Publisher
Basel, Switzerland: S. Karger AG
Journal title
Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Contents
Background/Aims: Intermittent hypoxia (IH) causes apoptosis in pancreatic β-cells, but the potential mechanisms remain unclear. Endoplasmic reticulum (ER) stress, autophagy, and apoptosis are interlocked in an extensive crosstalk. Thus, this study aimed to investigate the contributions of ER stress and autophagy to IH-induced pancreatic β-cell apop...
Alternative Titles
Full title
Intermittent-Hypoxia-Induced Autophagy Activation Through the ER-Stress-Related PERK/eIF2α/ATF4 Pathway is a Protective Response to Pancreatic β-Cell Apoptosis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3290317a0f64455697ac1785090d1d0e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3290317a0f64455697ac1785090d1d0e
Other Identifiers
ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.1159/000496047
