Effective gene editing by high-fidelity base editor 2 in mouse zygotes
Effective gene editing by high-fidelity base editor 2 in mouse zygotes
About this item
Full title
Author / Creator
Liang, Puping , Sun, Hongwei , Sun, Ying , Zhang, Xiya , Xie, Xiaowei , Zhang, Jinran , Zhang, Zhen , Chen, Yuxi , Ding, Chenhui , Xiong, Yuanyan , Ma, Wenbin , Liu, Dan , Huang, Junjiu and Songyang, Zhou
Publisher
Beijing: Higher Education Press
Journal title
Language
English
Formats
Publication information
Publisher
Beijing: Higher Education Press
Subjects
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Scope and Contents
Contents
Targeted point mutagenesis through homologous recombination has been widely used in genetic studies and holds considerable promise for repairing disease- causing mutations in patients. However, problems such as mosaicism and low mutagenesis efficiency continue to pose challenges to clinical applicaUon of such approaches. Recently, a base editor （BE...
Alternative Titles
Full title
Effective gene editing by high-fidelity base editor 2 in mouse zygotes
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_32befba0f8c44c9183474328e42ca512
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_32befba0f8c44c9183474328e42ca512
Other Identifiers
ISSN
1674-800X
E-ISSN
1674-8018
DOI
10.1007/s13238-017-0418-2
