Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts
Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts
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Publisher
Switzerland: MDPI
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Language
English
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Switzerland: MDPI
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Contents
Progeroid syndromes show features of accelerated ageing and are used as models for human ageing, of which Werner syndrome (WS) is one of the most widely studied. WS fibroblasts show accelerated senescence that may result from p38 MAP kinase activation since it is prevented by the p38 inhibitor SB203580. Thus, small molecule inhibition of p38-signal...
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Full title
Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts
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TN_cdi_doaj_primary_oai_doaj_org_article_3310edc11c814827b45083d157077305
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3310edc11c814827b45083d157077305
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ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph9020023
