Paromomycin production from Streptomyces rimosus NRRL 2455: statistical optimization and new synergi...
Paromomycin production from Streptomyces rimosus NRRL 2455: statistical optimization and new synergistic antibiotic combinations against multidrug resistant pathogens
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Response surface methodology (RSM) employing Box-Behnken design was used to optimize the environmental factors for the production of paromomycin, a 2 deoxystreptamine aminocyclitol aminoglycoside antibiotic, (2DOS-ACAGA) from Streptomyces (S.) rimosus NRRL 2455. Emergence of bacterial resistance caught our attention to consider the combination of a...
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Full title
Paromomycin production from Streptomyces rimosus NRRL 2455: statistical optimization and new synergistic antibiotic combinations against multidrug resistant pathogens
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TN_cdi_doaj_primary_oai_doaj_org_article_3349d8ea5df245fc8635b2f0bd183b31
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3349d8ea5df245fc8635b2f0bd183b31
Other Identifiers
ISSN
1471-2180
E-ISSN
1471-2180
DOI
10.1186/s12866-019-1390-1
