Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-facet...
Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
Thrombomodulin plays a vital role in maintaining intravascular patency due to its anticoagulant, antiinflammatory, and cytoprotective properties. However, under pathological conditions such as sepsis and systemic inflammation, endothelial thrombomodulin expression is downregulated and its function impaired. As a result, administering thrombomodulin...
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Full title
Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential
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TN_cdi_doaj_primary_oai_doaj_org_article_334c70317d2a4cc58dab121bb457adc2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_334c70317d2a4cc58dab121bb457adc2
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ISSN
1364-8535
E-ISSN
1364-8535,1466-609X
DOI
10.1186/s13054-019-2552-0