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Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-facet...

Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-facet...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_334c70317d2a4cc58dab121bb457adc2

Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential

About this item

Full title

Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential

Publisher

England: BioMed Central Ltd

Journal title

Critical care (London, England), 2019-08, Vol.23 (1), p.280-280, Article 280

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Thrombomodulin plays a vital role in maintaining intravascular patency due to its anticoagulant, antiinflammatory, and cytoprotective properties. However, under pathological conditions such as sepsis and systemic inflammation, endothelial thrombomodulin expression is downregulated and its function impaired. As a result, administering thrombomodulin...

Alternative Titles

Full title

Thrombomodulin in disseminated intravascular coagulation and other critical conditions—a multi-faceted anticoagulant protein with therapeutic potential

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_334c70317d2a4cc58dab121bb457adc2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_334c70317d2a4cc58dab121bb457adc2

Other Identifiers

ISSN

1364-8535

E-ISSN

1364-8535,1466-609X

DOI

10.1186/s13054-019-2552-0

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