In vivo therapeutic effects of affinity-improved-TCR engineered T-cells on HBV-related hepatocellula...
In vivo therapeutic effects of affinity-improved-TCR engineered T-cells on HBV-related hepatocellular carcinoma
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Author / Creator
Liu, Qi , Tian, Ye , Li, Yanyan , Zhang, Wei , Cai, Wenxuan , Liu, Yaju , Ren, Yuefei , Liang, Zhaoduan , Zhou, Peipei , Zhang, Yajing , Bao, Yifeng and Li, Yi
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publisher
England: BMJ Publishing Group Ltd
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Contents
BackgroundIn patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), virus-specific cytotoxic T lymphocytes (CTLs) fail to eliminate HCC cells expressing HBV antigens. As the expression of viral antigen in HBV-associated HCC may decrease to allow tumor to escape immune attacks, we hypothesized that an HBV surface antigen (HBsA...
Alternative Titles
Full title
In vivo therapeutic effects of affinity-improved-TCR engineered T-cells on HBV-related hepatocellular carcinoma
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_336cfd26b9ce46988230fde6f80ab0ae
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_336cfd26b9ce46988230fde6f80ab0ae
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2020-001748
