YAP-independent mechanotransduction drives breast cancer progression
YAP-independent mechanotransduction drives breast cancer progression
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Increased tissue stiffness is a driver of breast cancer progression. The transcriptional regulator YAP is considered a universal mechanotransducer, based largely on 2D culture studies. However, the role of YAP during in vivo breast cancer remains unclear. Here, we find that mechanotransduction occurs independently of YAP in breast cancer patient sa...
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Full title
YAP-independent mechanotransduction drives breast cancer progression
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TN_cdi_doaj_primary_oai_doaj_org_article_337f109f64fc4a38a5a3689ef568e48a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_337f109f64fc4a38a5a3689ef568e48a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09755-0
