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CAR‐T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions co...

CAR‐T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions co...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_338bcbe39cad4692acdfb83db0d67b2b

CAR‐T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions compared to those produced at relapse or following daratumumab treatment

About this item

Full title

CAR‐T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions compared to those produced at relapse or following daratumumab treatment

Publisher

United States: John Wiley & Sons, Inc

Journal title

EJHaem, 2022-08, Vol.3 (3), p.970-974

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Chimeric antigen receptor T cells (CAR‐T) have provided promising results in multiple myeloma (MM). However, many patients still relapse, pointing toward the need of improving this therapy. Here, we analyzed peripheral blood T cells from MM patients at different stages of the disease and investigated their phenotype and capacity to generate functio...

Alternative Titles

Full title

CAR‐T cells derived from multiple myeloma patients at diagnosis have improved cytotoxic functions compared to those produced at relapse or following daratumumab treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_338bcbe39cad4692acdfb83db0d67b2b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_338bcbe39cad4692acdfb83db0d67b2b

Other Identifiers

ISSN

2688-6146

E-ISSN

2688-6146

DOI

10.1002/jha2.479

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