Fungal dissemination is limited by liver macrophage filtration of the blood
Fungal dissemination is limited by liver macrophage filtration of the blood
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Fungal dissemination into the bloodstream is a critical step leading to invasive fungal infections. Here, using intravital imaging, we show that Kupffer cells (KCs) in the liver have a prominent function in the capture of circulating
Cryptococcus neoformans
and
Candida albicans
, thereby reducing fungal dissemination to target organs. C...
Alternative Titles
Full title
Fungal dissemination is limited by liver macrophage filtration of the blood
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3391e8a2cfc74237befa72af3155d7c0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3391e8a2cfc74237befa72af3155d7c0
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12381-5
