Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung...
Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung cancer
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London: BioMed Central Ltd
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Language
English
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London: BioMed Central Ltd
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Background Solid tumors subjected to intermittent hypoxia are characterized by resistance to chemotherapy and immune-killing by effector T-lymphocytes, particularly tumor-infiltrating V[gamma]9V[delta]2 T-lymphocytes. The molecular circuitries determining this double resistance are not known. Methods We analyzed a panel of 28 human non-small cell l...
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Mitochondrial ROS drive resistance to chemotherapy and immune-killing in hypoxic non-small cell lung cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_339f95a15a81485b9051ea494da23165
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_339f95a15a81485b9051ea494da23165
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-022-02447-6
