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IgD attenuates the IgM-induced anergy response in transitional and mature B cells

IgD attenuates the IgM-induced anergy response in transitional and mature B cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33bf5d14b2104b7e9e5694830f9f9ee0

IgD attenuates the IgM-induced anergy response in transitional and mature B cells

About this item

Full title

IgD attenuates the IgM-induced anergy response in transitional and mature B cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2016-11, Vol.7 (1), p.13381-13381, Article 13381

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Self-tolerance by clonal anergy of B cells is marked by an increase in IgD and decrease in IgM antigen receptor surface expression, yet the function of IgD on anergic cells is obscure. Here we define the RNA landscape of the
in vivo
anergy response, comprising 220 induced sequences including a core set of 97. Failure to co-express IgD with Ig...

Alternative Titles

Full title

IgD attenuates the IgM-induced anergy response in transitional and mature B cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_33bf5d14b2104b7e9e5694830f9f9ee0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33bf5d14b2104b7e9e5694830f9f9ee0

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms13381

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