A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
About this item
Full title
Author / Creator
Guo, Hou-Fu , Bota-Rabassedas, Neus , Terajima, Masahiko , Leticia Rodriguez, B. , Gibbons, Don L. , Chen, Yulong , Banerjee, Priyam , Tsai, Chi-Lin , Tan, Xiaochao , Liu, Xin , Yu, Jiang , Tokmina-Roszyk, Michal , Stawikowska, Roma , Fields, Gregg B. , Miller, Mitchell D. , Wang, Xiaoyan , Lee, Juhoon , Dalby, Kevin N. , Creighton, Chad J. , Phillips, George N. , Tainer, John A. , Yamauchi, Mitsuo and Kurie, Jonathan M.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Cancer cells are a major source of enzymes that modify collagen to create a stiff, fibrotic tumor stroma. High collagen lysyl hydroxylase 2 (LH2) expression promotes metastasis and is correlated with shorter survival in lung adenocarcinoma (LUAD) and other tumor types. LH2 hydroxylates lysine (Lys) residues on fibrillar collagen’s amino- and carbox...
Alternative Titles
Full title
A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
Authors, Artists and Contributors
Author / Creator
Bota-Rabassedas, Neus
Terajima, Masahiko
Leticia Rodriguez, B.
Gibbons, Don L.
Chen, Yulong
Banerjee, Priyam
Tsai, Chi-Lin
Tan, Xiaochao
Liu, Xin
Yu, Jiang
Tokmina-Roszyk, Michal
Stawikowska, Roma
Fields, Gregg B.
Miller, Mitchell D.
Wang, Xiaoyan
Lee, Juhoon
Dalby, Kevin N.
Creighton, Chad J.
Phillips, George N.
Tainer, John A.
Yamauchi, Mitsuo
Kurie, Jonathan M.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_33c609a5058f4848b50950a0e6133563
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33c609a5058f4848b50950a0e6133563
Other Identifiers
ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-01982-w
