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A helminth-derived suppressor of ST2 blocks allergic responses

A helminth-derived suppressor of ST2 blocks allergic responses

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33d967843f4146868a42245249420393

A helminth-derived suppressor of ST2 blocks allergic responses

About this item

Full title

A helminth-derived suppressor of ST2 blocks allergic responses

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2020-05, Vol.9

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The IL-33-ST2 pathway is an important initiator of type 2 immune responses. We previously characterised the HpARI protein secreted by the model intestinal nematode Heligmosomoides polygyrus, which binds and blocks IL-33. Here, we identify H. polygyrus Binds Alarmin Receptor and Inhibits (HpBARI) and HpBARI_Hom2, both of which consist of complement...

Alternative Titles

Full title

A helminth-derived suppressor of ST2 blocks allergic responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_33d967843f4146868a42245249420393

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33d967843f4146868a42245249420393

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.54017

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