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Oleanolic Acid Exerts a Neuroprotective Effect Against Microglial Cell Activation by Modulating Cyto...

Oleanolic Acid Exerts a Neuroprotective Effect Against Microglial Cell Activation by Modulating Cyto...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33dda819e50b43b9a24eaf3782f746ff

Oleanolic Acid Exerts a Neuroprotective Effect Against Microglial Cell Activation by Modulating Cytokine Release and Antioxidant Defense Systems

About this item

Full title

Oleanolic Acid Exerts a Neuroprotective Effect Against Microglial Cell Activation by Modulating Cytokine Release and Antioxidant Defense Systems

Publisher

Switzerland: MDPI

Journal title

Biomolecules (Basel, Switzerland), 2019-11, Vol.9 (11), p.683

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Microglia respond to adverse stimuli in order to restore brain homeostasis and, upon activation, they release a number of inflammatory mediators. Chronic microglial overactivation is related to neuroinflammation in Alzheimer’s disease. In this work, we show that oleanolic acid (OA), a natural triterpene present in food and medicinal plants, attenua...

Alternative Titles

Full title

Oleanolic Acid Exerts a Neuroprotective Effect Against Microglial Cell Activation by Modulating Cytokine Release and Antioxidant Defense Systems

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_33dda819e50b43b9a24eaf3782f746ff

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33dda819e50b43b9a24eaf3782f746ff

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom9110683

How to access this item