STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improvin...
STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networks
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England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Previous reports indicate a potential role for signal transducer and activator of transcription 3 (STAT3) in amyloid-β (Aβ) processing and neuritic plaque pathogenesis. In the present study, the impact of STAT3 inhibition on cognition, cerebrovascular function, amyloid pathology, oxidative stress, and neuroinflammation was studied using in vitro an...
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STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networks
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TN_cdi_doaj_primary_oai_doaj_org_article_33e4d8191d1d435b9f18d426a1f31ded
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_33e4d8191d1d435b9f18d426a1f31ded
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-021-01293-5
