Deciphering the tumor immune microenvironment of imatinib-resistance in advanced gastrointestinal st...
Deciphering the tumor immune microenvironment of imatinib-resistance in advanced gastrointestinal stromal tumors at single-cell resolution
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Author / Creator
Liu, Xuechao , Yu, Jing , Li, Yi , Shi, Hailei , Jiao, Xuelong , Liu, Xiaodong , Guo, Dong , Li, Zequn , Tian, Yulong , Dai, Fan , Niu, Zhaojian and Zhou, Yanbing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The heterogeneous nature of tumors presents a considerable obstacle in addressing imatinib resistance in advanced cases of gastrointestinal stromal tumors (GIST). To address this issue, we conducted single-cell RNA-sequencing in primary tumors as well as peritoneal and liver metastases from patients diagnosed with locally advanced or advanced GIST....
Alternative Titles
Full title
Deciphering the tumor immune microenvironment of imatinib-resistance in advanced gastrointestinal stromal tumors at single-cell resolution
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3411f096297342f794c8249133b2e733
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3411f096297342f794c8249133b2e733
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-024-06571-3
