Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross...
Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses
About this item
Full title
Author / Creator
Boyoglu-Barnum, Seyhan , Hutchinson, Geoffrey B. , Boyington, Jeffrey C. , Moin, Syed M. , Gillespie, Rebecca A. , Tsybovsky, Yaroslav , Stephens, Tyler , Vaile, John R. , Lederhofer, Julia , Corbett, Kizzmekia S. , Fisher, Brian E. , Yassine, Hadi M. , Andrews, Sarah F. , Crank, Michelle C. , McDermott, Adrian B. , Mascola, John R. , Graham, Barney S. and Kanekiyo, Masaru
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The conserved hemagglutinin (HA) stem has been a focus of universal influenza vaccine efforts. Influenza A group 1 HA stem-nanoparticles have been demonstrated to confer heterosubtypic protection in animals; however, the protection does not extend to group 2 viruses, due in part to differences in glycosylation between group 1 and 2 stems. Here, we...
Alternative Titles
Full title
Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses
Authors, Artists and Contributors
Author / Creator
Hutchinson, Geoffrey B.
Boyington, Jeffrey C.
Moin, Syed M.
Gillespie, Rebecca A.
Tsybovsky, Yaroslav
Stephens, Tyler
Vaile, John R.
Lederhofer, Julia
Corbett, Kizzmekia S.
Fisher, Brian E.
Yassine, Hadi M.
Andrews, Sarah F.
Crank, Michelle C.
McDermott, Adrian B.
Mascola, John R.
Graham, Barney S.
Kanekiyo, Masaru
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_341c5ca3cd954a0f92613862f3db746e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_341c5ca3cd954a0f92613862f3db746e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-14579-4
