Multiscale modelling of chromatin 4D organization in SARS-CoV-2 infected cells
Multiscale modelling of chromatin 4D organization in SARS-CoV-2 infected cells
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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SARS-CoV-2 can re-structure chromatin organization and alter the epigenomic landscape of the host genome, but the mechanisms that produce such changes remain unclear. Here, we use polymer physics to investigate how the chromatin of the host genome is re-organized upon infection with SARS-CoV-2. We show that re-structuring of A/B compartments can be...
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Full title
Multiscale modelling of chromatin 4D organization in SARS-CoV-2 infected cells
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TN_cdi_doaj_primary_oai_doaj_org_article_34229b608a134e5c8d7dae241dafcf19
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34229b608a134e5c8d7dae241dafcf19
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-48370-6
