Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2...
Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors
About this item
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Author / Creator
Grandits, Melanie , Palhares, Lais C G F , Osborn, Gabriel , Chauhan, Jitesh , Stoker, Katie , Sow, Heng Sheng , Adams, Rebecca , McCraw, Alex J , Chenoweth, Alicia , Vlasova, Sofia , López-Abente, Jacobo , Ilieva, Kristina M , Birtley, James , Tsoka, Sophia , Hardaker, Elizabeth , FitzGerald, Kevin , Karagiannis, Sophia N and Bax, Heather J
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publication information
Publisher
England: BMJ Publishing Group Ltd
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Scope and Contents
Contents
BackgroundAnti-human epidermal growth factor receptor 2 (HER2) IgG1-based antibody therapies significantly improve cancer prognosis, yet intrinsic or acquired resistance to fragment antigen-binding (Fab)-mediated direct effects commonly occurs. Most resistant tumors retain antigen expression and therefore remain potentially targetable with anti-HER...
Alternative Titles
Full title
Fc-mediated immune stimulating, pro-inflammatory and antitumor effects of anti-HER2 IgE against HER2-expressing and trastuzumab-resistant tumors
Authors, Artists and Contributors
Author / Creator
Palhares, Lais C G F
Osborn, Gabriel
Chauhan, Jitesh
Stoker, Katie
Sow, Heng Sheng
Adams, Rebecca
McCraw, Alex J
Chenoweth, Alicia
Vlasova, Sofia
López-Abente, Jacobo
Ilieva, Kristina M
Birtley, James
Tsoka, Sophia
Hardaker, Elizabeth
FitzGerald, Kevin
Karagiannis, Sophia N
Bax, Heather J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3467691d09cf46bf8392dc7b7fab649f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3467691d09cf46bf8392dc7b7fab649f
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2024-010945