The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its mali...
The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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The microenvironment provides a functional substratum supporting tumour growth. Hyaluronan (HA) is a major component of this structure. While the role of HA in malignancy is well-defined, the mechanisms driving its biosynthesis in cancer are poorly understood. We show that the eukaryotic translation initiation factor eIF4E, an oncoprotein, drives H...
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The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity
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TN_cdi_doaj_primary_oai_doaj_org_article_347003db749b4cfea541aa4f5080caa2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_347003db749b4cfea541aa4f5080caa2
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.29830
