Androgen receptor and MYC equilibration centralizes on developmental super-enhancer
Androgen receptor and MYC equilibration centralizes on developmental super-enhancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Androgen receptor (AR) in prostate cancer (PCa) can drive transcriptional repression of multiple genes including
MYC
, and supraphysiological androgen is effective in some patients. Here, we show that this repression is independent of AR chromatin binding and driven by coactivator redistribution, and through chromatin conformation capture met...
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Full title
Androgen receptor and MYC equilibration centralizes on developmental super-enhancer
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TN_cdi_doaj_primary_oai_doaj_org_article_347b7d0db16a4ab1a53e337245e1df79
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_347b7d0db16a4ab1a53e337245e1df79
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27077-y
