Billion‐Scale Expansion of Functional hiPSC‐Derived Cardiomyocytes in Bioreactors Through Oxygen Con...
Billion‐Scale Expansion of Functional hiPSC‐Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation
About this item
Full title
Author / Creator
Vicente, Pedro , Inocêncio, Lara R. , Ullate‐Agote, Asier , Louro, Ana F. , Jacinto, João , Gamelas, Beatriz , Iglesias‐García, Olalla , Martin‐Uriz, Patxi San , Aguirre‐Ruiz, Paula , Ríos‐Muñoz, Gonzalo R. , Fernández‐Santos, María Eugenia , Mil, Alain , Sluijter, Joost P. G. , Prósper, Felipe , Vega, Manuel M Mazo , Alves, Paula M. and Serra, Margarida
Publisher
Germany: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
Germany: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Generation of upscaled quantities of human‐induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM), for therapeutic or testing applications, is both expensive and time‐consuming. Herein, a scalable bioprocess for hiPSC‐CM expansion in stirred‐tank bioreactors (STB) is developed. By combining the continuous activation of the Wnt pathway, thr...
Alternative Titles
Full title
Billion‐Scale Expansion of Functional hiPSC‐Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation
Authors, Artists and Contributors
Author / Creator
Inocêncio, Lara R.
Ullate‐Agote, Asier
Louro, Ana F.
Jacinto, João
Gamelas, Beatriz
Iglesias‐García, Olalla
Martin‐Uriz, Patxi San
Aguirre‐Ruiz, Paula
Ríos‐Muñoz, Gonzalo R.
Fernández‐Santos, María Eugenia
Mil, Alain
Sluijter, Joost P. G.
Prósper, Felipe
Vega, Manuel M Mazo
Alves, Paula M.
Serra, Margarida
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_34860ff4c9af47758f0baafb83d35216
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34860ff4c9af47758f0baafb83d35216
Other Identifiers
ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202410510
