Stabilizing mutation of CTNNB1/beta-catenin and protein accumulation analyzed in a large series of p...
Stabilizing mutation of CTNNB1/beta-catenin and protein accumulation analyzed in a large series of parathyroid tumors of Swedish patients
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Publisher
London: BioMed Central
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English
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London: BioMed Central
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Background
Aberrant accumulation of β-catenin plays an important role in a variety of human neoplasms. We recently reported accumulation of β-catenin in parathyroid adenomas from patients with primary hyperparathyroidism (pHPT). In
CTNNB1
exon 3, we detected a stabilizing mutation (S37A) in 3 out of 20 analyzed adenomas. The aim of the pre...
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Full title
Stabilizing mutation of CTNNB1/beta-catenin and protein accumulation analyzed in a large series of parathyroid tumors of Swedish patients
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TN_cdi_doaj_primary_oai_doaj_org_article_349cfc28a2844133beb9de0141815a5c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_349cfc28a2844133beb9de0141815a5c
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-7-53
