Synthesis of novel mono- and bis-pyrazolylthiazole derivatives as anti-liver cancer agents through E...
Synthesis of novel mono- and bis-pyrazolylthiazole derivatives as anti-liver cancer agents through EGFR/HER2 target inhibition
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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3-Bromoacetyl-4-(2-naphthoyl)-1-phenyl-1H-pyrazole (6) was synthesized from 2-acetylnaphthalene and was used as a new key building block for constructing the title targets. Thus, the reaction of 6 with the thiosemicarbazones 7a–d and 9–11 afforded the corresponding simple naphthoyl-(3-pyrazolyl)thiazole hybrids 8a–d and 12 ~ 14. The symmetric bis-(...
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Synthesis of novel mono- and bis-pyrazolylthiazole derivatives as anti-liver cancer agents through EGFR/HER2 target inhibition
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TN_cdi_doaj_primary_oai_doaj_org_article_34aea7c94024461aa2faadd7a4a5e8ca
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34aea7c94024461aa2faadd7a4a5e8ca
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ISSN
2661-801X
E-ISSN
2661-801X
DOI
10.1186/s13065-023-00921-6
