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Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity pr...

Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34b30dc350304d7da86e97eaeab203a7

Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles

About this item

Full title

Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-11, Vol.8 (1), p.1232-9, Article 1232

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Plasmodium
parasites have extensive needs from their host hepatocytes during the obligate liver stage of infection, yet there remains sparse knowledge of specific host regulators. Here we assess 34 host-targeted kinase inhibitors for their capacity to eliminate
Plasmodium yoelii
-infected hepatocytes. Using pre-existing activity profiles o...

Alternative Titles

Full title

Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_34b30dc350304d7da86e97eaeab203a7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34b30dc350304d7da86e97eaeab203a7

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-01345-2

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