Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity pr...
Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Plasmodium
parasites have extensive needs from their host hepatocytes during the obligate liver stage of infection, yet there remains sparse knowledge of specific host regulators. Here we assess 34 host-targeted kinase inhibitors for their capacity to eliminate
Plasmodium yoelii
-infected hepatocytes. Using pre-existing activity profiles o...
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Full title
Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles
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TN_cdi_doaj_primary_oai_doaj_org_article_34b30dc350304d7da86e97eaeab203a7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34b30dc350304d7da86e97eaeab203a7
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01345-2