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Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophren...

Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophren...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34c57aa0fb3a4c8899725ee021846a0b

Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia

About this item

Full title

Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-05, Vol.11 (1), p.2329-2329, Article 2329

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Impaired cognitive functioning is a core feature of schizophrenia, and is hypothesized to be due to myelination as well as interneuron defects during adolescent prefrontal cortex (PFC) development. Here we report that in the apomorphine-susceptible (APO-SUS) rat model, which has schizophrenia-like features, a myelination defect occurred specificall...

Alternative Titles

Full title

Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_34c57aa0fb3a4c8899725ee021846a0b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_34c57aa0fb3a4c8899725ee021846a0b

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-16218-4

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